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Filtered Search Results
Medchemexpress LLC Tipiracil | 183204-74-2 | 99.98% | C9H11ClN4O2 | 200 MG
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Tipiracil is a thymidine phosphorylase (TPase) inhibitor intended for research use only. It increases trifluridine exposure by inhibiting its metabolism by thymidine phosphorylase. The combination of Trifluridine and Tipiracil is a new oral treatment for metastatic colorectal cancer.
- Thymidine phosphorylase (TPase) inhibitor
- Increases trifluridine exposure
- Prevents degradation of FTD
- New oral treatment for metastatic colorectal cancer
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Medchemexpress LLC Bromocriptine mesylate | 22260-51-1 | 99.9% | 750.70 | 50 MG
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Bromocriptine mesylate is a potent dopamine D2/D3 receptor agonist, binding to the D2 dopamine receptor with a pKi of 8.05. It is permeable to the blood-brain barrier. It stimulates [35S]-GTPγS binding at D2 dopamine receptors and acts as a strong inhibitor of brain nitric oxide synthase (neuronal NOS) and a potent inhibitor of CYP3A4.
- Potent dopamine D2/D3 receptor agonist
- Permeable to the blood-brain barrier
- Stimulates [35S]-GTPγS binding at D2 dopamine receptors
- Strong inhibitor of brain nitric oxide synthase (neuronal NOS)
- Potent inhibitor of CYP3A4
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Medchemexpress LLC Firmonertinib (mesylate) | 2130958-55-1 | 100.0% | 664.70 | 100 MG
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Firmonertinib mesylate is an orally active, mutant-selective, and blood-brain barrier penetrant EGFR inhibitor. It inhibits EGFR active mutations as well as the T790M acquired resistant mutation. Firmonertinib mesylate has the potential for the research of cancer diseases, especially advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation.
- Orally active
- Mutant-selective
- Blood-brain barrier penetrant EGFR inhibitor
- Inhibits EGFR active mutations
- Inhibits T790M acquired resistant mutation
- Potential for research of cancer diseases, especially advanced non-small cell lung cancer (NSCLC) with EGFR ex20ins mutation
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000702662 SULFO GALACTOSYLCERA 1MG
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Apexbio Technology LLC Fluocinolone Acetonide 67-73-2 200mg
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Fluocinolone Acetonide (67-73-2) is a glucocorticoid receptor (GR) agonist targeting the GR It is designed to modulate intracellular signaling pathways mediated by the GR thereby regulating inflammatory response and influencing lipid metabolism by reducing lipid accumulation in tissues Fluocinolone Acetonide exerts its biological activity primarily through activation of the GR In cellular assays Fluocinolone Acetonide demonstrates stimulation of proliferation in dental pulp cells (DPCs) Based on these pharmacological properties Fluocinolone Acetonide holds research potential in studies of dental tissue regeneration and repair as well as in investigations of preventative and therapeutic strategies for chemotherapy-induced peripheral neuropathy
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Medchemexpress LLC (-)-Huperzine A | 102518-79-6 | 99.7% | 242.32 | 200 MG
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(-)-Huperzine A | 102518-79-6 | 99.7% | 242.32 | 200 MG
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Medchemexpress LLC NCT-503 | 1916571-90-8 | 99.7% | 408.48 g/mol | C20H23F3N4S | 200 MG
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NCT-503 is a small-molecule inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 2.5 μM, used as a research tool to probe serine biosynthesis pathways and PHGDH-dependent cancer biology in vitro and in vivo.
- Potent PHGDH inhibition with IC50 2.5 μM.
- High selectivity against other dehydrogenases and minimal GPCR cross-reactivity.
- Demonstrated activity in PHGDH-dependent cell lines and tumor xenograft models.
- Solid form with high purity suitable for biochemical and cellular assays.
- Recommended storage conditions for long-term stability.
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Ambeed AMBEED
5000886395 7-AMINOISOQUINOLINE 5G
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Ambeed AMBEED
NC4004586 DANGLIPR CAS2230198-02-2 200MG
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eMolecules 1261462-15-0 | 5-HYDROXYQUINOLINE-4-CARBOXYLIC ACID | MFCD18417134 | 1g
Ambeed | (S)-5-Benzyl-5-azaspiro[2.4]heptan-7-amine | 100mg | 650570763 | A827644 | 144282-35-9 | MFCD17926316 | 202.301 | C13H18N2
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Medchemexpress LLC 2-Hydroxyquinoline | 59-31-4 | 145.16 | 25 G
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2-Hydroxyquinoline is an inhibitor of α-glucosidase and α-amylase, with IC50 values of 64.4 μg/mL and 130.5 μg/mL respectively. This off-white to light yellow solid can be utilized in diabetes research.
- Inhibitor of α-glucosidase (IC50: 64.4 μg/mL)
- Inhibitor of α-amylase (IC50: 130.5 μg/mL)
- Off-white to light yellow solid
- Soluble in DMSO at 100 mg/mL
- Purity (HPLC): 99.44%
- Stable under recommended storage conditions
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Medchemexpress LLC 2-Aminoquinoline | 580-22-3 | 144.17 | 100 G
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2-Aminoquinoline is a promising compound as a bioavailable nNOS inhibitor, despite exhibiting low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. It demonstrates antiviral activity against the vaccinia virus and has potential for research into antineurodegenerative agents. This product is for research use only.
- Antiviral activity against vaccinia virus.
- Potential for research into antineurodegenerative agents.
- For research use only.
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Innovative Research Inc Rat Sprg Dwly Albumin 200mg
Rat Sprague Dawley Albumin 200mg - Rat Sprague Dawley Albumin from Innovative Research has been purified from US origin Rat Plasma using proprietary chromatographic and cold ethanol fractionation methods. This is a salt free lyophilized powder with a purity of >95%. This product is useful as a positive control for ELISA and western blot and for a variety of in vitro and in vivo applications including blocking, cell signaling, drug studies, protein-protein interactions, protein stabilization, receptor binding, and tissue culture. This is an ultra-pure preparation, especially as compared to commercially available heat-shock preparations of Albumin, which are less pure and may contain denatured albumin.
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Medchemexpress LLC Ro 31-9790 (GI4747) | 145337-55-9 | 99.4% | 315.41 g/mol | C15H29N3O4 | 50 MG
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Ro 31-9790 is a synthetic matrix metalloproteinase (MMP) inhibitor used as a research reagent to probe MMP activity, protease-mediated ectodomain shedding, and related cellular pathways. It is supplied as a high-purity solid for laboratory studies and includes handling and storage recommendations to preserve stability.
- High purity, suitable for biochemical and cellular assays.
- Molecular weight 315.41 g/mol and formula C15H29N3O4 for compound identification.
- Off-white to light yellow solid appearance for easy visual confirmation.
- Recommended storage at 4°C; protect from light and store under inert gas; in solvent, store at -80°C (6 months) or -20°C (1 month).
- Soluble in DMSO with supplier-provided concentration guidance for assay preparation.
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Ambeed AMBEED
5000885098 2-METHYL-8-QUINOLINOL 100G
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